The Boreal OnTarget™ allele enrichment system allows researchers to detect and sequence both known and unknown rare somatic mutations by performing selective wild-type allele depletion in a simple, 1 hour process. By improving the sensitivity of downstream detection assays or sequencing, OnTarget™ can enable non-invasive monitoring of cancer and improve effectiveness of personalized treatment.
Early access applications for the OnTarget™ system are now being accepted with placements in mid-2012. View our product specification or contact a sales representative for more information.
Rare mutation detection |
Why wild-type rejection? |
Novel variant discovery |
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Rapid and parallelized enrichment with OnTarget™ improves sensitivity 100-fold or greater, regardless of downstream assay. See application |
Single nucleotide selectivity with wild-type allele depletion improves the detection and sequencing of rare mutations. Learn more |
Multiplexed enrichment of mutation hot-spots by wild-type allele depletion enables discovery of novel mutations. See application |
Resources
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OnTarget™ Early Access System Specification |
February 2012 | PLoS ONE |
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