Boreal’s technology enables efficient nucleic acid extraction from your most challenging samples. Our superior ability to recover low abundance DNA from heavily inhibited samples produces yields that are typically at least 10x greater than the best columns or phenol-chloroform procedures.

Life Sciences Research

Extraction of DNA and RNA from challenging samples, the Aurora instrument’s ability to remove all inhibitors makes it ideal for various applications in life science research.

Soil & Environmental

Extraction of DNA or RNA from a variety of environmental samples including humic-rich high biomass agricultural soils; low biomass soil and sand from the atacama desert or antartic tundra; oil sands and hydrocarbon-rich sediments; heavily contaminated water; and stool.

Agriculture Biotechnology

Purification of inhibited samples such as plant and pericarp tissues using the Aurora instrument results in high yields of purified DNA that is ready for downstream applications such as PCR and genotyping.

Forensics

Boreal’s technology can be used to purify low abundance and heavily inhibited samples from forensic casework or forensic anthropology.

 


 

Scientific Publications

October 2010 | Cold Spring Harbor Protocols

Efficient genomic DNA extraction from low target concentration bacterial cultures using SCODA DNA extraction technology | PDF | HTML

September 2009 | PNAS

Nonlinear electrophoretic response yields a unique parameter for separation of biomolecules | PDF | HTML

February 2008 | JALA

An Instrument for Automated Purification of Nucleic Acids from Contaminated Forensic Samples | PDF | HTML

January 2005 | Electrophoresis

Novel electrophoresis mechanism based on synchronous alternating drag perturbation | PDF | HTML

Recent publications featuring Aurora

Zaremba-Niedzwiedzka et. al. | January 2017 | Nature

Asgard archaea illuminate the origin of eukaryotic cellular complexity | HTML

Datema et. al. | November 2016 | BioRxiv

The megabase-sieze fungal genome of Rhizoctonia solani assembled from nanopore reads only | HTML

De Santi et. al. | January 2016 | BMC Biochemistry

Characterization of a cold-active and salt tolerant esterase identified by functional screening of Arctic metagenomic libraries | HTML

Charlop-Powers et. al. | July 2014 | Current Opinion in Microbiology

Metagenomic small molecule discovery methods | HTML

Lam et. al. | June 2014 | PLOS One

Evaluation of a Pooled Strategy for High-Throughput Sequencing of Cosmid Clones from Metagenomic Libraries | HTML

S. Schmedes et. al. | December 2012 | Int’l Journal of Legal Medicine

Effective removal of co-purified inhibitors from extracted DNA samples using synchronous coefficient of drag alteration (SCODA) technology | HTML

J. J. Schwartz et. al. | October 2012 | PNAS

Capturing native long-range contiguity by in situ library construction and optical sequencing | HTML

R. L. Welch et. al. | July 2012 | Lab on a Chip

Denaturation mapping of Saccharomyces cerevisiae | HTML

C. Neish et. al. | April 2012 | ABSCICON 2012

A new approach for DNA detection in Mars analogue soils using SCODA | Poster

S. Schmedes et. al. | March 2012 | University of North Texas Health Sciences Center

The application of SCODA technology towards the extraction and purification of DNA from challenging forensic and medically-relevant samples | Poster

K. Engel et. al. | Jan 2012 | Journal of Microbiological Methods

Nonlinear electrophoresis for purification of soil DNA for metagenomics | HTML