Boreal’s technology enables efficient nucleic acid extraction from your most challenging samples. Our superior ability to recover low abundance DNA from heavily inhibited samples produces yields that are typically at least 10x greater than the best columns or phenol-chloroform procedures.
Life Sciences Research
Extraction of DNA and RNA from challenging samples, the Aurora instrument’s ability to remove all inhibitors makes it ideal for various applications in life science research.
Soil & Environmental
Extraction of DNA or RNA from a variety of environmental samples including humic-rich high biomass agricultural soils; low biomass soil and sand from the atacama desert or antartic tundra; oil sands and hydrocarbon-rich sediments; heavily contaminated water; and stool.
- Direct Extraction of Low Molecular Weight DNA 300 bp to 30 kb from Environmental Samples
- Direct Extraction of High Molecular Weight DNA 700 bp to 50 kb from Environmental Samples
- Extraction of Ultra High Molecular Weight DNA 30 kb up to 1 Mb from Environmental Samples
- DNA Clean-up from Contaminated Water Samples
- High Molecular Weight DNA Purification from Stool Samples
Purification of inhibited samples such as plant and pericarp tissues using the Aurora instrument results in high yields of purified DNA that is ready for downstream applications such as PCR and genotyping.
Boreal’s technology can be used to purify low abundance and heavily inhibited samples from forensic casework or forensic anthropology.
October 2010 | Cold Spring Harbor Protocols
September 2009 | PNAS
February 2008 | JALA
January 2005 | Electrophoresis
Recent publications featuring Aurora
Zaremba-Niedzwiedzka et. al. | January 2017 | Nature
Asgard archaea illuminate the origin of eukaryotic cellular complexity | HTML
Datema et. al. | November 2016 | BioRxiv
The megabase-sieze fungal genome of Rhizoctonia solani assembled from nanopore reads only | HTML
De Santi et. al. | January 2016 | BMC Biochemistry
Characterization of a cold-active and salt tolerant esterase identified by functional screening of Arctic metagenomic libraries | HTML
Charlop-Powers et. al. | July 2014 | Current Opinion in Microbiology
Metagenomic small molecule discovery methods | HTML
Lam et. al. | June 2014 | PLOS One
Evaluation of a Pooled Strategy for High-Throughput Sequencing of Cosmid Clones from Metagenomic Libraries | HTML
S. Schmedes et. al. | December 2012 | Int’l Journal of Legal Medicine
Effective removal of co-purified inhibitors from extracted DNA samples using synchronous coefficient of drag alteration (SCODA) technology | HTML
J. J. Schwartz et. al. | October 2012 | PNAS
Capturing native long-range contiguity by in situ library construction and optical sequencing | HTML
R. L. Welch et. al. | July 2012 | Lab on a Chip
Denaturation mapping of Saccharomyces cerevisiae | HTML
C. Neish et. al. | April 2012 | ABSCICON 2012
A new approach for DNA detection in Mars analogue soils using SCODA | Poster
S. Schmedes et. al. | March 2012 | University of North Texas Health Sciences Center
The application of SCODA technology towards the extraction and purification of DNA from challenging forensic and medically-relevant samples | Poster
K. Engel et. al. | Jan 2012 | Journal of Microbiological Methods
Nonlinear electrophoresis for purification of soil DNA for metagenomics | HTML