At Boreal Genomics, we are delivering innovative technologies that enable genetic analysis of the most challenging samples in life science research and clinical diagnostics. Our methods revolutionize approaches to total nucleic acid extraction and sequence-based allele enrichment with single nucleotide resolution.
Nucleic acid extraction
Our commercially available Aurora system enables recovery of low abundance nucleic acids, even from heavily inhibited samples including challenging environmental matrices like oil sands, soil, sediments and contaminated water; stool; plant tissues and seeds; and difficult forensic casework specimens. Our unique SCODA technology also enables recovery of very high molecular weight DNA from 50 kb to over 1 Mb for cloning, library generation, and integration with other nucleic acid analysis technologies.
Allele enrichment
The OnTarget™ allele enrichment system revolutionizes detection and sequencing of rare somatic mutations from frozen tissue, FFPE or plasma samples. By enriching mutant alleles with highly selective wild-type allele depletion, OnTarget™ enables reliable detection of both known and previously unknown rare variants below 0.01% abundance.
Now available through an early access program, OnTarget™ provides 100-fold or greater improvements to the sensitivity of downstream detection assays or sequencing of rare tumor mutations. Applications for the allele enrichment technology include non-invasive monitoring of cancer, pathogen detection, ultra-pure oligo synthesis, fetal nucleic acid enrichment, methylation-based enrichment, and any area of nucleic acid research where target is overwhelmed by background.
Our Team
At Boreal, we believe in taking a highly collaborative approach in developing and building our products. Our team of molecular biologists, physicists and engineers closely listen to our customers, understanding their scientific challenges and believe in working with them to deliver innovative solutions for life sciences research and clinical diagnostics.
Founded by leading researchers from the University of British Columbia in 2007, Boreal has grown to establish corporate headquarters in the San Francisco Bay Area in mid-2011. Boreal holds an exclusive license to a broad patent portfolio from the University of British Columbia on the novel Synchronous Coefficient of Drag Alteration (SCODA) technology.
