At Boreal Genomics, we are delivering innovative technologies that enable genomic analysis of the most challenging samples in life science research and clinical diagnostics. Our methods revolutionize approaches to total nucleic acid extraction and the targeted enrichment of specific DNA sequences.
Nucleic acid extraction is commercially available in the Aurora nucleic acid purification system which enables recovery of high yield and purity nucleic acids for successful PCR analysis or sequencing of challenging samples such as soil and environmental matrices rich in inhibitors including oil sands, sediments and contaminated water; stool; plant tissues and seeds; and difficult forensic casework specimens. Our technology also enables recovery of high molecular weight DNA from 50 kb – 1 Mb for cloning, library generation, and integration with other direct analysis technologies.
Allele enrichment is a second-generation technology that is capable of unprecedented enrichment of nucleic acids, with a demonstrated ability to enrich for point mutations against background by 10,000 fold without PCR amplification. We are in the process of developing this technology to improve detection and sequencing of extremely rare somatic mutations present in blood plasma, tumor samples, and cell lines. Our scientists are also collaborating with clinicians in improving the detection of infectious diseases by applying our technology to enrich for pathogen sequences from whole blood.
We believe in taking a highly collaborative approach in building products. Our team of molecular biologists, physicists and engineers enjoy listening to our customers, understanding their scientific challenges and believe in working with them to deliver innovative solutions for life sciences research and clinical diagnostics.
Founded by leading researchers at the University of British Columbia in 2007, Boreal has grown to establish corporate headquarters in the San Francisco Bay Area in 2011. Boreal holds an exclusive license to a broad patent portfolio from the University of British Columbia on the novel Synchronous Coefficient of Drag Alteration (SCODA) technology.
Learn More
